ABSTRACT
We describe the clinico-pathological features and discuss the possible pathogenetic mechanism of thyroid papillary carcinoma arising in a branchial cleft cyst. This has been described only once previously in the literature.
Subject(s)
Humans , Male , Adult , Thyroid Gland/pathology , Branchioma/pathology , Carcinoma, Papillary/pathology , Head and Neck Neoplasms/pathology , JamaicaABSTRACT
Idiopathic focal and segmental glomerulosclerosis (IFSGS) in a predominantly black population does not appear to behave any differently than in Caucasian patients. Response to steroid therapy and cyclophosphamide had favourable prognostic significance. There may be a subgroup of IFSGS which responds more slowly to steroids. The duration of steroid therapy should extend beyond four months
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Glomerulosclerosis, Focal Segmental/drug therapy , Glomerulosclerosis, Focal Segmental/epidemiology , Cyclophosphamide/therapeutic use , Prognosis , Steroids/therapeutic use , Fatal Outcome , Black PeopleABSTRACT
Of the twenty-nine children with solid tumours treated at the University Hospital of the West Indies (UHWI) between January, 1972 and December, 1991, there were twenty-eight cases of nephroblastoma and one of mesoblastic nephroma. Peak incidence was between the ages of two and four years. Twenty-five children had radical nephrectomy while one had bilateral partial nephrectomy. In thirteen cases, pre-operative chemotherapy and radiotherapy was used. Post-operative chemotherapy and radiotherapy were used in 24 and 13 cases, respectively. Stage of the tumour was the most decisive factor influencing the outcome. Whereas there was 100 per cent cure rate in Stages I and II, Stage III had only a 55.5 per cent survival rate and non of the Stage IV survived. Bilateral (Stage V) tumours are curable if individual tumours are localised, as in one of the two cases. The benign mesoblastic nephroma, in a one-month-old infant, was cured by nephrectomy alone. While the present therapy of radical nephrectomy along with combination chemotherapy is satisfactory for early stages, more aggressive adjuvant therapy is needed for improving the results in Stages III and IV
Subject(s)
Infant , Child, Preschool , Child , Humans , Male , Female , Wilms Tumor , Kidney Neoplasms , Prognosis , Retrospective Studies , Treatment Outcome , Nephroma, Mesoblastic , Wilms Tumor/diagnosis , Wilms Tumor/mortality , Wilms Tumor/therapy , Kidney Diseases/diagnosis , Kidney Diseases/mortality , Kidney Diseases/therapy , Neoplasm StagingABSTRACT
A case of inflammatory pseudotumour of the spleen in a 34-year-old female patient is described. We have briefly reviewed the literature on the subject and discussed aetiopathogenesis, pre-operative differential diagnosis and treatment modalities.